Rituximab, a CD20-specific monoclonal antibody that depletes B cells, has shown promising results in patients with relapsing-remitting multiple sclerosis. Studies of experimental autoimmune ...

Antibody-producing B cells begin to malfunction early after infection with HIV, for reasons that are poorly understood. In August 14 on-line Proceedings of the National Academy of Sciences Susan Moir ...

It is likely that B-cell-derived regulatory IL-10 has evolved to serve distinct immune functions, and that these functions are in turn carefully regulated in a cell-subset- and context-dependent ...

Scientists mapped how the human immune system evolves from birth to old age, revealing key changes that influence health, ...

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell ...

Glyco-immunology provides a new approach to treating autoimmunity by enhancing depletion of activated memory B cells, the pathogenic subset of B cells associated with disease progression and often ...