This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

The Mt. Sinai study could open the door to future therapies for Alzheimer’s, amyotrophic lateral sclerosis, brain cancer, and ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering ...

Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...

Traumatic brain injury is a leading cause of death and disability in the world. Blunt force trauma to the brain, often from a ...

Scientists have developed a lipid nanoparticle system that enables mRNA to cross the blood-brain barrier, a long-standing challenge in n.

近年来，随着技术的发展，研究人员在药物递送和疾病治疗方面不断突破传统方法的局限。尤其是在治疗神经系统疾病和代谢疾病时，如何有效地将药物输送到大脑，成为了医学领域的一个重大挑战。传统的药物递送方式，如口服、注射等，都面临着血脑屏障（Blood-Brai ...

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the ...

BioArctic signed the first deal for its “brain transporter” with Bristol Myers Squibb late last year. The deal is worth up to $1.4bn and allows the US drugmaker to start trials using the technology to ...

Scientists explore how the immune and nervous systems constantly communicate, influencing brain diseases, behavior, and ...

Researchers at the National University of Singapore have reported crossing the blood–brain barrier with help from a modified Lactobacillus plantarum. By delivering an appetite-regulating hormone ...