This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering ...

Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...

The Mt. Sinai study could open the door to future therapies for Alzheimer’s, amyotrophic lateral sclerosis, brain cancer, and ...

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the ...

Scientists have developed a lipid nanoparticle system that enables mRNA to cross the blood-brain barrier, a long-standing challenge in n.

BioArctic signed the first deal for its “brain transporter” with Bristol Myers Squibb late last year. The deal is worth up to $1.4bn and allows the US drugmaker to start trials using the technology to ...

Addressing the harmful chemical processes that accompany blunt force trauma to the brain can reduce the risk of long-term ...

Investigators reported that the amount of nano and microplastics detected in brain samples is increasing but urge caution in ...

Brain inflammation, while a crucial part of the body's immune response, takes on a detrimental role in Alzheimer's disease.

Scientists explore how the immune and nervous systems constantly communicate, influencing brain diseases, behavior, and ...

Researchers at the National University of Singapore have reported crossing the blood–brain barrier with help from a modified Lactobacillus plantarum. By delivering an appetite-regulating hormone ...