During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

由于基因组异质性，单细胞复制时间（scRT）在癌症中的研究具有挑战性。在这里，作者开发了MnM，这是一种机器学习工具，可以提供异质性分辨率的scRT文件，并将其应用于包括肿瘤、细胞系和患者来源的异种移植物在内的大型单细胞数据集。

到目前为止，DNA和RNA的表观遗传学研究是作为独立的系统进行的。这两种机制似乎分别发挥作用，各自在基因调控过程的不同阶段发挥自己的作用。也许这是个错误。在《细胞》（Cell）杂志上发表的一篇文章中，由ULB医学院癌症表观遗传学实验室、ULB癌症研究 ...

Replication of DNA DNA replication is the process by which a cell makes an identical copy of its DNA. Gene expression Only a fraction of the genes possessed by any particular cell will be expressed.

A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication. Cell lines ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

When cells express specific genes that characterise a certain type of cell we say that a cell has become differentiated. Structure and replication of DNA DNA is the molecule that holds the ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...