It is unclear which intestinal epithelial cell-derived cytokines can precisely regulate intestinal stem cell (ISC) commitment toward specific mature cells. Here, authors identify an epithelial ...

we delve into the intricate mechanisms employed by intestinal cells to secure the vital nutrients and metabolic resources essential for preserving intestinal stem cell fate and function. And, how ...

His research aims to identify the role of extracellular vesicles from intestinal epithelial cells ... following allogeneic stem cell transplantation. Understanding how IEC-EVs influence immune ...

By comparing young and aged mouse intestinal tissues, the researchers uncovered critical insights into the interplay between these signaling pathways in supporting stem cell maintenance over time.