Background and aim: The importance of the hepatocyte ploidisation pattern to the control of cell proliferation and differentiation has been well established. However, there are no data that have ...

Background and objective Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic ...

Objective An international meeting was organised to develop consensus on (1) the landmarks to define the gastro-oesophageal junction (GOJ), (2) the occurrence and pathophysiological significance of ...

2 Department of Primary Care and Public Health Sciences, King's College London, London, UK Methods Material and Methods: This was a single centre, double blind, randomised, placebo controlled trial ...

These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) ...

Objective Patients with increased PD-L1 + host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is ...

BACKGROUND/AIMS Vascular endothelial growth factor (VEGF) plays a key role in regulation of tumour associated angiogenesis. In the current study we analysed expression of VEGF and its receptors in ...

1 Nashville VA Medical Center and the Departments of Surgery and Cell and Developmental Biology, Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA 2 ...

Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...

Correspondence to Dr Noel F C C de Miranda, Pathology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; N.F.de_Miranda{at}lumc.nl Objective Biological insights into the stepwise ...

Background Chicoric acid (CA), a hydroxycinnamic acid, has been reported to possess anti-inflammation activities. However, the specific mechanisms by which CA influences dextran sulfate sodium ...

1 Liver Unit, Department of Medicine A, Imperial College School of Medicine, St Mary’s Hospital Campus, South Wharf Street, London W2 1PG, UK 2 Department of Hepatobiliary Surgery, Royal Free Hospital ...