There is emerging evidence indicating that ncRNAs can also extensively participate in a wide spectrum of cellular events, ranging from embryogenesis to tumorigenesis, and it is known that ncRNAs exert ...

vanderbilt.edu Design Tff1-knockout (Tff1-KO) mice, immunohistochemistry, luciferase reporter, qRT-PCR, immunoblot, and phosphatase assays were used to examine the role of TFF1 on β-catenin signalling ...

Scientists have uncovered a key mechanism in jellyfish embryos that provides new insights into how the body plan of these ...

Scientists have uncovered a key mechanism in jellyfish embryos that provides new insights into how the body plan of these ...

为此， ...

Wnt–β-catenin signalling regulates stem cell renewal, development and tissue homeostasis. In this Review, the authors examine recent findings concerning Wnt protein production, receptor ...

【导读】 ...

Patient enrollment is expected to begin in the first half of 2025, subject to final protocol review by regulatory authorities ...

近期，哥本哈根大学诺和诺德基金会蛋白质研究中心的研究人员在npj Precision Oncology期刊上发表了一篇题为 “Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma” ...

好书推荐！《动物行为实验指南》电子版pdf，网盘发货《动物行为实验指南》共674页，涵盖了常见的实验动物，如小鼠、大鼠和斑马鱼，详细描述了每一种行为测试的实验设计、测试设备、实验流程、评估指标、预期结果、常见问题及解决方法、数据分析、模型应用与局限性 ...

PPAR 在调节脂质代谢、葡萄糖代谢以及控制能量平衡方面发挥着关键作用，同时也参与细胞增殖、分化、凋亡和血管生成等其他生物学过程。PPAR 与多种人类疾病相关，其在动脉粥样硬化、炎症、免疫、癌症以及肥胖、糖尿病等各种代谢紊乱疾病的发生发展中所起的作用已得到充分证实。

Figure 1: Transgene expression and phenotype. Figure 2: K14.MYC2 mice exhibit impairment in wound healing. Figure 3: K14.MYC2 primary keratinocytes exhibit a defect in migration. Figure 4: K14 ...