AMP-activated protein kinase (AMPK), a key metabolic regulator, plays an essential role in the maintenance of energy balance in response to stress. Tuberculosis (TB), primarily caused by the pathogen ...

Adenosine monophosphate-activated protein kinase (AMPK) is a significant energy sensor in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved catabolic process that ...

Here is how to find them in 3 easy steps: The usp10.dll is missing or not designed to run on Windows or any other related errors can prevent you from launching programs, installing or even ...

At the forefront of this revolutionary approach is a team of Canadian researchers who uncovered how low AMPK levels correlate with weight gain—often overshadowing the traditional “eat less ...

Ubiquitylation is a reversible post-translational modification involved in a myriad of cellular functions. A superfamily of approximately 100 ubiquitin-specific proteases, called deubiquitylating ...

本研究为通过 agd1/usp10/mettl13-cd44-pstat3/pi3k-akt 级联反应介导的多西他赛化疗的分子机制提供了新的见解，为 crpc 的基因治疗提供了新的靶点。 【参考 ...

Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India ...

【导读】大多数前列腺癌患者不可避免地会发展为去势抵抗性前列腺癌（CRPC），此时多西他赛等化疗药物成为一线治疗手段。然而，在最初一段治疗有效期后，通常会出现化疗耐药性。 1月14日，上海交通大学研究团队在期刊《Journal of Experimental & Clinical Cancer ...