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α-Synuclein 调控黑色素瘤核仁 DNA 双链断裂修复:帕金森病与黑色素瘤 ...
帕金森病(PD)与黑色素瘤的关联机制不明,研究人员开展 α-Synuclein(αSyn)在黑色素瘤中作用的研究。结果显示,αSyn 在黑色素瘤核仁富集,参与 DNA 双链断裂(DSB)修复,影响细胞增殖等。该研究为理解二者关联提供依据,有重要意义。
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