we investigated the role of the RIP3 axis in OA pathogenesis. Methods Experimental OA was induced in wild-type or Rip3 knockout mice by surgery to destabilise the medial meniscus (DMM) or the ...

Adenoviruses (AdVs) are icosahedral viruses with double-stranded DNA (dsDNA) genomes. Genome packaging in AdV is thought to be similar to that seen in dsDNA containing icosahedral bacteriophages and ...

Correspondence to Varpu Elenius, Department of Paediatrics, Turku University Hospital, Box 52, 20521 Turku, Finland; varpu.elenius{at}utu.fi ...

Research demonstrates that the SARS-CoV-2 protein ORF8 drives osteoclastogenesis, establishing a direct link between viral infection and bone loss. A new study shows that activation of vagal ...

Human adenovirus serotype 5 (Ad5), which induces T-cell response, is a widely used viral vector. In this study, we aimed to evaluate the efficacy of a multi-antigenic recombinant Ad5 vectored vaccine ...

A woman in her 70s presented to the hospital being generally unwell 8 days following the first dose of the AstraZeneca COVID-19 vaccination. She was in stage III acute kidney injury (AKI) with ...

The Maine CDC is excited to announce that we are modernizing our Tuberculosis (TB) reporting system. Currently, inactive TB (also known as Latent TB Infection or LTBI) cases and suspect and confirmed ...

This important study provides insights into the physiological role of RIPK1 in liver physiology, particularly during short-term fasting. The discovery that RIPK1 deficiency sensitizes the liver to ...