Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

A research group from Nagoya City University has elucidated the significance of birth in the maintenance of neural stem cells (NSCs).The ... In the adult mammalian brain, NSCs are retained in ...

That dogma changed ∼25 years ago with the identification of neural stem cells (NSCs) in the adult rodent forebrain. However, unlike rapidly self-renewing mature tissues (e.g., blood, intestinal crypts ...

Considering that glutamine metabolism also regulates the functions of tissue stem cells other than NSCs, our findings enhance our understanding of the pivotal role of birth in tissue homeostasis ...

Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem ...

Aging and neurological diseases limit this exit from quiescence, so we have a great need to study adult neural stem cells in their different cell states. Our goal was to create a new tool that ...

Tetramethylpyrazine induces the release of BDNF from bone marrow mesenchymal stem cells by activating the PI3K/Akt/CREB pathway for neural differentiation ... and the functional role of adult ...

Mesenchymal stem cells are adult stem cells found in several places ... approaches and found them beneficial for people with MS. Neural stem cells are derived from other types of stem cells ...

Neural stem cells (NSCs) contribute to plasticity and repair of the adult brain. Niches harboring NSCs regulate stem cell self-renewal and differentiation. We used comprehensive and untargeted ...

Department of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an 710032, ...

Now, scientists at Gladstone Institutes and the regenerative medicine company SanBio have shown that a cell therapy derived from stem cells can ... restoring balance in neural networks.