Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

The aldosterone-renin ratio (ARR) has gained popularity as a screening test for primary hyperaldosteronism, a probably underdiagnosed cause of hypertension. However, studies have yielded varying ...

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Casarosa pointed to aldosterone synthase inhibitor BI 690517, which showed its potential as a dual therapy with Jardiance at the American Society of Nephrology (ASN) Kidney Week 2023 congress in a ...