(Nasdaq: GANX) (“Gain”, or the “Company”), a clinical-stage biotechnology company leading the discovery and development of the next generation of allosteric small molecule therapies ... Key biomarkers ...

School of Environment and Energy Engineering, Gwangju Institute of Science and Technology (GIST), 123 Cheomdan-gwagiro, Buk-gu, Gwangju 61005, Republic of Korea Research Center for Innovative Energy ...

A new study has identified an enzyme that plays an important role ... for which USP5 is essential, for the first time. We assume that inhibiting the loss of USP5 or therapeutically increasing ...

Centre for Endocrinology, William Harvey Research Institute, Bart’s and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, U.K. School ...

Herein, we tested the hypotheses that (i) the ether lipid profiles in activated B cells depend on their expression of the biosynthetic enzyme PexRAP [alternatively referred to as acyl/alkyl-DHAP ...

Both synthesis and degradation of the (p)ppGpp alarmone nucleotide are mediated by RelA-SpoT Homolog (RSH) enzymes which can be broadly divided in two classes ... Instead, we argue that it is driven ...

In the present study, we aimed to study the effect of GPX4 activator on the AA metabolic network and inflammation related pathways. Using combined computational and experimental screen, we identified ...

An enzyme called gamma-secretase cuts other proteins in cells into smaller pieces. Like most enzymes, gamma-secretase is expected to move through several different three-dimensional shapes to perform ...