Enzymes can be regulated by various means, such as allosteric regulation (binding of effector molecules), covalent modification (e.g., phosphorylation), and changes in pH or temperature. The Michaelis ...

Allosteric effectors that are not competitive can serve as effective activators of weak enzymes or as inhibitors of overactive enzymes. Allosteric activators or inhibitors induce small ...

Another current area of research for LLAB involves unraveling the mechanistic principles underlying positive allosteric modulators of lecithin-cholesterol acyltransferase (LCAT). LCAT is an enzyme ...