Limb-girdle muscular dystrophy type 2D (LGMD2D/R3) is a rare genetic disorder caused by mutations in the SGCA gene, leading to defective folding and the loss of functional α-sarcoglycan, with ...

Alibaba Group Holding Limited, through its subsidiaries, provides technology infrastructure and marketing reach to help merchants, brands, retailers, and other businesses to engage with their ...

It’s been a minute since Lifehacker looked at the slang of Generation Z—long enough that Generation Alpha has had time to develop and spread some of its own special buzzwords and jargon.

The Walt Disney Company operates as an entertainment company worldwide. It operates through three segments: Entertainment, Sports, and Experiences. The company produces and distributes film and ...

There are several subtypes of muscular dystrophies, which are categorized based on genetics and molecular pathogenesis ( Table 1). Here we discuss the relevant proteins and protein complexes.

In cancer, the impact on cellular fitness of copy-number gains affecting collaterally-amplified genes remains poorly understood compared to oncogenes. Here, the authors integrate genomic data from ...

familial acute respiratory distress syndrome, ANLN-related, dog (MONDO:1012930) neuromuscular channelopathy, KCNG1-related, cattle (MONDO:1012911) progressive retinal atrophy, FAM161A-related, dog ...

Considering that the expression of tissue nonspecific alkaline phosphatases can be up-regulated by cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β), a subset of ...

The term dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders that are characterized by ventricular dilation and depressed myocardial performance in the absence of ...

Genetics is the branch of science concerned with genes, heredity, and variation in living organisms. It seeks to understand the process of trait inheritance from parents to offspring, including ...

While the virus is generally found in wild birds and poses risk only to poultry, its spread to a new range of mammals may pave the way for new mutations that could increase its lethality. In 2024, the ...