Anti-CD20 mAbs were originally created to treat B cell proliferative diseases such as non-Hodgkin's lymphoma and chronic ...

Based on the previous reports that citrullinated antigens are present in joints ... After washing with PBS-T, the slides were incubated with the mAb 12G1 (1:50) overnight at 4°C. A biotinylated horse ...

The candidate antibodies were then orthogonally validated in two independent groups of patients with SSc. Mice were immunised with the target antigen, which was subsequently evaluated by histological ...

Objective Autoantibodies against antigens carrying distinct post-translational modifications (PTMs), such as citrulline, homocitrulline or acetyllysine, are hallmarks of rheumatoid arthritis (RA). The ...

Anti-CD19 chimeric antigen receptor (CD19-CAR)-engineered T cells are approved therapeutics for ... a transmembrane domain-dependent heterodimeric association of the CAR with the endogenous CD28 ...

A study published in December by Duke professor Rohit Singh and his team proposes a new computational model called antibody ...

For this purpose, a doctor may order anti-dsDNA, anti-Sm, Sjögren's antigens (SSA, SSB), Scl-70 antibodies, anti-centromere, anti-histone, and anti-RNP. The ANA blood test can seem complicated. The ...

Multi-laser picodroplets can be used in single cell analysis, sorting and dispensing - discover how in this article.

This ligand–receptor pair mediates endothelial and antigen-presenting ... steroids seemed to antagonize the anti-rejection effect. Monkeys treated with antibody against CD154 remained healthy ...

Creative Diagnostics introduces comprehensive Vaccine Development CRO Services. NEW YORK, NY, UNITED STATES, February 22, 2025 /EINPresswir ...

Chimeric antigen receptor (CAR ... Western blot analysis was performed and immunoblotting with anti-CD3 zeta monoclonal antibody produced bands of predicted size (57.86 kDa) for the CD5CAR ...

New antibody AHA-1031 shows potential in treating non small cell lung cancer resistant to immunotherapy, offering new hope.