We focused on the ability of CMPNs to induce apoptosis through the CHOP-mediated ER stress pathway and PARP ... Primary antibodies against CHOP (1:200; A0221, Abclonal) and Cleaved-PARP (1:200; 5625S, ...
A prominent example is the stratification of epithelial ovarian cancer (EOC) patients with homologous recombination deficiency (HRD) characterized by mutations in DNA damage repair genes such as BRCA1 ...