Steroids take an indirect route to treat inflammation by inhibiting the production of arachidonic acid. But when you make an incision, you have already started that pathway, and the arachidonic ...

School of Biotechnology and Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China School of Biotechnology and Key ...

AT-rich interactive domain-containing protein 1A (ARID1A) encodes a switch/sucrose nonfermentable (SWI/SNF) complex and is mutated in around 10% of colorectal cancers. ARID1A deficiency damages DNA ...

Liqun Yu, postdoctoral fellow in the Zhang lab at Baylor. "The prevailing perspective in our field has focused on the role of fatty acid metabolism in regulating the immune response and ...

Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, United States Laboratory of Systems Pharmacology, Harvard ...

LOX 酶可催化分子氧插入 PUFA 特定的酰基链，生成高度富集的氢过氧化物衍生物。比如，花生四烯酸（Arachidonic acid，AA）和亚油酸（Linoleic acid，LA）可分别转化为氢过氧化二十碳四烯酸（Hydroperoxyeicosatetraenoic acid，HPETEs）和羟基十八碳二烯酸（Hydroxyoctadecadienoic acids ...

《Cell death pathway regulation by fatty acid metabolism?related genes in neuroblastoma: a multi?omics analysis identifying CHD5 as a novel biomarker》解读 在儿童肿瘤的世界里，神经母细胞瘤（Neuroblastoma）就像一个神秘又危险的 ...

Docosahexaenoic acid (DHA) is a type of omega-3 fatty acid that’s particularly important for brain health. DHA and arachidonic acid (AA) are deposited into the lipids of cell membranes that form ...

They also noted increased activity of the arachidonic acid signaling pathway—a target for aspirin, which is used as an experimental preventive treatment for individuals affected by FAP. These ...

In addition, we also conducted metabolic pathway enrichment analysis on known metabolites that have a causal relationship ... Biosynthesis of unsaturated fatty acids, Arachidonic acid metabolism, ...