Table 1. Summary of medical therapy (chemotherapy and aromatase inhibitors) and measurements of cognitive functioning (neuropsychological testing and functional imaging) and potential ...

[14] Just as these five studies show conflicting results for hormone therapies including tamoxifen and aromatase inhibitors, they all vary in study design and analysis. However, significant data ...

The trial evaluated the efficacy of imlunestrant, an oral selective estrogen receptor degrader (SERD), compared with fulvestrant (Faslodex) in patients who had previously been treated with CDK4/6 ...

Ellen Behrend, VMD, PhD, MS, DACVIM (SAIM), discusses what to monitor in cats on SGLT2 inhibitors, and how it differs from the monitoring required for patients on insulin Monitoring feline patients ...

NEW YORK – The National Institute for Health and Care Excellence (NICE) is recommending Novartis' Kisqali (ribociclib) plus an aromatase inhibitor for certain patients with early-stage breast cancer ...

Compared with DPP-4 inhibitors, SGLT2 inhibitors and GLP-1RAs conferred lower risks for COPD exacerbation among patients with type 2 diabetes. Among patients with type 2 diabetes (T2D) and active ...

In recent years, structure-based drug design has facilitated the development of lysine-targeting covalent inhibitors. The CoDEL technology is rapidly emerging as a key platform for covalent drug ...

Bruton tyrosine kinase (BTK) inhibitors are typically used to treat B-cell malignancies, but they have also recently attracted interest for their potential in treating the autoimmune disorder multiple ...

Other companies with KRAS inhibitors in the pipeline include Eli Lilly/Incyte, MSD, Novartis, Roche/Chugai, Revolution Medicines, and Quanta Therapeutics. GlobalData recently predicted that the ...

In this guide, we’ll explain the OKR framework and when OKRs should be used. We’ll also provide several examples of objectives and key results so that you can better understand how to ...