How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

The following is a summary of “Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma,” published in the January 2025 issue of Urology by Chen et al. Clear cell ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Endometrial cancer (EC) ranks as the second most prevalent gynecologic malignancy globally, with approximately 189,000 new ...

In summary, we believe that sequence and functional ... directed toward their relevance in the cell cycle, transcription or other cellular processes. In addition, this simplified nomenclature ...

Jan. 23, 2025 — There's a downside to being a powerful alpha male -- at least if you're a baboon. Studies show that despite their high rank, the No. 1 males in baboon society are also some of ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

Financially, UroGen has a market cap of $464mn and a cash runway of 8-9 quarters, despite facing patent challenges from Teva.

The relationship between autophagy and cell death is complex because autophagy constitutes an adaptive response to different kinds of stress by which the cells avoid cell death; yet, in some ...

Researchers at UT Southwestern identified how SNX17 and Retriever interact to regulate endosomal recycling, a crucial process ...

Previous studies have shown that this modification is required for the dynamic regulation of essential cellular functions, such as the cell's life cycle, and even how cells break down sugar to ...

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.