Cells activate various pathways to counter DNA replication stress. Using Replication-IDentifier (Repli-ID), the authors identified 423 genes, including LGE1 and ROX1, linking epigenetic and ...

The non-descript, pill-shaped cell is why we understand fundamental life processes (think DNA replication and transcription).

like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments strive to block a virus or halt its replication. However, viruses are ...

Researchers say if their results are confirmed through further study they are optimistic the approach could be used to treat chronic infections for the first time.

15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

Recent innovations in DNA-modifying will revolutionize the treatment of many diseases and prompt crucial discussions.

This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

It emerges that excess fusion is averted by stress-activated regulators, preventing the potentially harmful release of mitochondrial DNA. Visualizing RNA molecules in live cells remains a ...

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

Large molecules with multiple binding sites can be flexible, but the impact of this flexibility on network formation hasn’t ...

The Double Helix” paints Watson and Crick as lone pioneers while downplaying the contributions of others, most notably of ...

Nucleoside analogs are transformative in cancer and antiviral therapies, offering new avenues for treatment despite ...