Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...

New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...

As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site ...

A groundbreaking discovery by researchers in South Korea has revealed a potential game-changer in cancer treatment through a ...

and directed differentiation of pluripotent stem cells or lineage conversion of accessible somatic cells to induced Schwann cells, with the potential of “unlimited” supply. All approaches require a ...

Up to date, a growing body of preclinical and clinical studies have demonstrated the potential application of MSCs and their cell-free ... and histopathological scores of lupus nephritis by directly ...

Downstream of the pre-BCR, SYK (spleen tyrosine kinase) has a central role in the activation of pathways that regulate the proliferation and differentiation of pre-B cells. In the context of ...

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to ...

Danés, principal investigator of the Cancer and Stem Cell Biology Lab at the Champalimaud Foundation, in Lisbon, has shown ...

“For endangered species, this technique provides a potential method for producing offspring through unisexual reproduction, ...