A team of scientists has uncovered the mechanism of cellular uptake for large and polar drugs and devised a novel strategy to ...

Researchers have made a major breakthrough that could transform IV medications into oral treatments for diseases like brain ...

Scientists have found a surprising new way to make certain cancer drugs work dramatically better – by helping them get inside ...

A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body.

Researchers have made a major breakthrough with the potential to turn intravenous drugs into oral treatments for diseases ...

Breakthrough research could make any IV drug able to be taken orally for a range of hard-to-treat cancers and other diseases, and redefine how medicines are designed, evaluated and delivered.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Toll-like receptor 4 (TLR4) signaling at the ...

Apr. 18, 2025 — Scientists report adaptive divergence in cryptic color pattern is underlain by two distinct, complex chromosomal rearrangements, where millions of ...

A new strategy for delivering bulky PROTACs to cancerous cells successfully utilizes the CD36 protein pathway on cells’ surfaces.

Ideally, such strategies would target the disease-related subtype of clathrin-mediated endocytosis while allowing the cell to take up nutrients and remain healthy. Previous large-scale siRNA ...

Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...