Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein response (UPR mt) serves as an important retrograde regulatory pathway that ...

This organization has no public members. You must be a member to see who’s a part of this organization.

They show that rather than exclusively providing energy to the cell, glycolysis is able to control, at different stages of early embryonic development, cell fate decisions and the end-state appearance ...

More information: Reuben Franklin et al, Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate, Genes & Development (2025). DOI ...

Tet1/3 are dispensable for CD8 effector and memory T cell fate during peripheral T cell priming. Tet1/3 license the chromatin landscape of TCR-responsive genes during thymic T cell maturation. To shed ...

Count on Thermo Scientific™ IntelliStack™ Incubator Shakers and CO2 Incubator Shakers to provide accurate, adjustable and reproducible growth conditions for your mammalian, bacterial and yeast cell ...