For years chemokines have primarily been thought of as instigators of leukocyte trafficking in the immune system. Fresh data forces their role in cancer to be revisited and greatly broadened.

So far, nanobodies targeting receptors such as EGFR, HER2, VEGFR2, c-Met, CXCR7 or ligands (HGF and chemokines ... based therapeutic accumulation at the tumor. The size and shape of the molecule ...

This review will discuss therapeutic effects of the most influential chemokines with a special ... complete eradication of the established solid tumors [89] CCL21 + mitomycin C Breast cancer ...

Caption Tumors can drive thrombosis by releasing chemokines, secreted proteins that can circulate to the lung. This image of a lung sample shows how immune cells called macrophages release small ...

The study, published Feb. 11 in Cell, shows that tumors drive clot formation (thrombosis) by releasing chemokines, secreted proteins which then circulate to the lung. Once there, the chemokines ...

Bolt Biotherapeutics, Inc., announced today that the target of their worldwide co-development collaboration with Toray Industries, Inc. is Caprin-1, a novel cancer target discovered by Toray. The ...