Renal hypoplasia, defined as abnormally small kidneys with normal morphology and reduced nephron number, is a common cause of pediatric renal failure and adult-onset disease. Genetic studies ...

FIGURE 1. Overview of early kidney development in mouse. At embryonic day 11.0, the ureteric bud (UB) grows out from the nephric duct (ND) and enters the metanephric mesenchyme (MM). By E11.5, the UB ...

Cardiovascular diseases are the number one cause of death worldwide and greatly impact quality of life and medical costs. Enormous effort has been made in research to obtain new tools for efficient ...