Renal hypoplasia, defined as abnormally small kidneys with normal morphology and reduced nephron number, is a common cause of pediatric renal failure and adult-onset disease. Genetic studies ...

The proximal tubules, responsible for reabsorbing over 80% of the glomerular filtrate, are heavily reliant on active transport processes, which necessitate a higher mitochondrial density compared to ...

FIGURE 1. Overview of early kidney development in mouse. At embryonic day 11.0, the ureteric bud (UB) grows out from the nephric duct (ND) and enters the metanephric mesenchyme (MM). By E11.5, the UB ...

Most cancers are named after the part of the body where the cancer first begins, and kidney cancer is no exception. Kidney cancer begins in the kidneys—two large, bean-shaped organs—one located to the ...

Renal tubule epithelial cells can be oval ... [9] Casts are formed in the distal tubules and collecting ducts where Tamm–Horsfall proteins precipitate and entrap cells present in urine.

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Acute renal failure is caused by damage to the kidneys, which can occur as a result of blood loss, toxins, or physical damage to the kidneys. Acute renal failure occurs rapidly, causing generalized ...

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This happens even when not crying. The eye is not red and the eyelid is not swollen. Both sides are blocked in 30% of these children. Caused by blockage of the lacrimal duct. This duct carries ...

In its early stages, kidney disease may not cause any symptoms or signs. However, as it progresses, it can cause symptoms such as itchy skin, pruritus, and a rash. Around 35.5 million adults in ...