The human complement system is a complex defense system that helps protect the body from pathogens. Similar to the coagulation system, the complement system consists of a cascade of proteases that ...

The Complement group, headed by Prof. Seppo Meri, has for long had an interest in sorting out how and why the complement system contributes to disease pathogenesis, how the system is controlled and ...

Previous work uncovered the role of the complement system in neuroinflammation and synaptic loss in neurodegenerative disorders such as Alzheimer’s disease (AD). The third component, C3, central in ...