Nanomedicine is a multidisciplinary research field with an integration of traditional sciences such as chemistry, physics, biology and materials science. The application of nanomedicine for lung ...
The increasing use of recombinantly expressed therapeutic proteins in the pharmaceutical industry has highlighted issues such as their stability during long-term storage and means of efficacious ...
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Mca-SEVKMDAEFRK (Dnp) RR-NH2 分子结构中,N 端为强荧光的 7 - 甲氧基香豆素(Mca)基团,通过酰胺键依次连接一系列氨基酸残基(丝氨酸、谷氨酸、缬氨酸、赖氨酸、甲硫氨酸、天冬氨酸、丙氨酸、谷氨酸、苯丙氨酸、精氨酸、赖氨酸),其中赖氨酸的侧链氨基连接了 ...
Drug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People’s Republic of China Department of Chemistry, National University of ...
紫杉醇(PTX)作为一种有效的抗癌药物,广泛应用于多种癌症的治疗。然而,PTX的水溶性极低(0.1 μg/mL),传统制剂中常使用Cremophor EL作为溶剂,但其会引起严重的副作用,如过敏反应和药物抗性。因此,开发一种能够提高PTX溶解性和安全性的新型递送系统成为 ...
Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. In recent years, many different materials have been explored as ...