“EGFR” stands for “epidermal growth factor receptor.” The EGFR gene controls the production of EGFR proteins, which are found in both healthy and abnormal cells. They help cells grow and divid ...

DelveInsight's "TAGRISSO Market Size, Forecast, and Market Insight Report" highlights the details around TAGRISSO, a kinase inhibitor of the EGFR, which binds irreversibly to certain mutant forms of ...

An EGFR gene mutation is one of the biomarkers a doctor often tests for after confirming a diagnosis of non-small cell lung cancer (NSCLC). Biomarkers can help guide treatment. EGFR mutations ...

TAGRISSO has become a standard treatment due to its strong efficacy in both first-line and adjuvant settings. The growing prevalence of EGFR mutations, a rise in lung cancer diagnoses, and broader ...

1Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

CISH+ rates were associated with T3–T4 status. Compared with FISH assay, CISH reached a sensitivity of 37.5% and specificity of 100%. Conclusions There is no association between EGFR expression and ...

为了解决这一难题，南京医科大学第一附属医院等机构的研究人员展开了深入研究。他们的研究成果发表在《Molecular Cancer》上，为非小细胞肺癌 EGFR-TKI 耐药的治疗开辟了新道路。 研究人员首先利用生物信息学分析，对来自 Gene Expression Omnibus（GEO）数据库的多个微阵列数据集进行挖掘。他们发现，烟酰胺 N - 甲基转移酶（NNMT）在 EGFR-TKI ...

During a live event, Alexander I. Spira, MD, PhD, and participants discuss efficacy, adverse events, and sequencing of EGFR-mutated NSCLC treatments. Nataliya Melnyk, MD: I have not used the ...

Johnson & Johnson’s (J&J) Lazcluze (lazertinib) has been approved by the Medicines and Healthcare products Regulatory Agency ...