南京鼓楼医院东南大学医学院肾脏病研究所的研究人员 Xue-qi Li 等人在《Acta Pharmacologica Sinica》期刊上发表了题为 “Neddylation of RhoA impairs its protein degradation and promotes renal interstitial fibrosis progression in diabetic ...

In MSCs, asprosin prevents these cells from oxidative stress-induced apoptosis and death by activating ERK1/2-SOD2 pathway. In the skeletal muscle, asprosin activates PKCδ/SERCA2-mediated ER ...

Competing interests AM is a member of the scientific advisory board of AlloMek Therapeutics, LLC, a privately held pharmaceutical company developing small molecules targeting ERK1/2 signalling. All ...

Objective Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in ...

Nintendo Switch 2 is finally confirmed. After literal years of unverified rumors, dubious leaks and copious amounts of online speculation, Nintendo has lifted the lid on its next-generation ...

In malignant melanoma, extracellular stimulus signals are transmitted into cells through receptors on the membrane and can activate TWIST1 through RAS-RAF-MEK1/2-ERK1/2, PI3K-AKT-NFKB, and STAT3 ...

Death Stranding 2 has been confirmed for PS5, and Kojima Productions is yet to reveal whether it will arrive on other platforms. When Death Stranding launched in 2019, it did so as a PS4 exclusive.

在结核病防控形势严峻的当下，韩国忠南国立大学医学院微生物学与医学科学系的研究人员取得了一项重要成果，相关论文 “Novel fusion protein REA induces robust prime protection against tuberculosis in mice” 发表于 npj Vaccines 期刊。该研究开发出一种新型融合蛋白疫苗候选物 ...

Some eight years since the Nintendo Switch was released, we have finally got an official look at the Nintendo Switch 2. In a rather brief trailer, Nintendo showed off its next-generation gaming ...

However, the Nintendo Switch 2 will not arrive in your mailbox for at least the next few months. While we have a better idea of what it looks like, we still have to rely on leaks and rumors for ...

After hours: February 3 at 4:18:53 PM EST Loading Chart for ERAS ...

After seven years on the market, 146 million systems, and more than 1 billion games sold, Nintendo has finally announced the Nintendo Switch 2. The rumor mill was heating up in January ...