Disrupting any of the three systems that contribute to epigenetic alterations can cause abnormal activation or silencing of genes. Such disruptions have been associated with cancer, syndromes ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the ...

Recent research has provided strong evidence suggesting that a variety of epigenetic mechanisms may underlie transgenerational inheritance. These include differential DNA methylation, histone ...

A new study suggests that diets high in fast food, processed red meat, and soda but low in fruits and vegetables may be ...

Of particular interest is the silencing of tumor-suppressor genes by epigenetic alteration. Recent progress in understanding epigenetic modification and gene silencing has led to new opportunities ...

Discover how the revolutionary field of epigenetics and the development of an epigenetic map of the human genome are paving ...

Despite their differences, both mechanisms contribute to molecular aging. Researchers have long speculated about a potential connection between genetic mutations and epigenetic alterations. The new ...

Precision oncology is a cancer treatment approach that considers individual genetics, environmental exposures, and lifestyle factors to tailor the most ...

Epigenetic mechanisms in general, and chromatin alterations in particular, are involved in all aspects of cancer development and progression. A number of elegantly conducted translational studies have ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the ...

Epigenetics refers to chemical alterations to genes that promote cancer growth and spread without mutating the DNA. "For solid tumors—the major killers in cancer—there is a tremendous unmet ...