Disrupting any of the three systems that contribute to epigenetic alterations can cause abnormal activation or silencing of genes. Such disruptions have been associated with cancer, syndromes ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Colorectal cancer is typically diagnosed after age 50, but in recent years the disease has been increasingly found in younger ...

A new study suggests that diets high in fast food, processed red meat, and soda but low in fruits and vegetables may be ...

discuss how epigenetic alterations arise in MDS and contribute to its pathogenesis and then discuss the mode of action of HMA in MDS. New methods based on next-generation sequencing or microarrays ...

Researchers have long speculated about a potential connection between genetic mutations and epigenetic alterations. The new study provides evidence for this link. Using data from the Cancer Genome ...

Epigenetics refers to chemical alterations to genes that promote cancer growth and spread without mutating the DNA. "For solid tumors—the major killers in cancer—there is a tremendous unmet ...

Epigenetic modifiers ... profiling revealed comparable decreases in H3K36me3 levels and gene expression alterations in both models. Notably, many collagen genes, which are often long and highly ...

Researchers identified genes that could explain why some assisted reproductive technologies, like IVF, carry a higher risk of growth and metabolic issues in offspring.

Maternal stress could leave epigenetic imprints on genes in the placenta associated with cortisol — a necessary hormone for ...