Objectives To investigate the effect of the L-arginine metabolism on arthritis and inflammation-mediated bone loss. Methods L-arginine was applied to three arthritis models (collagen-induced arthritis ...

Natural product synthesis aims to prepare a complex target ... Here, the authors elucidate the biosynthetic pathway of ECH in Cistanche tubulosa and synthesize 23 PhGs in tobacco.

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Ach, Acetylcholine; ANP, Atrial Natriuretic Peptide; Epi, Epinephrine; NE, Norepinephrine ... Simplified schematic of neural, hormonal, redox, and immune signaling pathways activated in adrenal ...

Objective The extent to which tryptophan (Trp) metabolism alterations explain or influence the outcome of inflammatory bowel diseases (IBDs) is still unclear. However, several Trp metabolism ...

Conclusion Oxidative stress, especially through purine metabolism pathway, is a major metabolic event during reperfusion and may contribute to the ischaemia reperfusion injury of lung grafts. Data are ...

This role is proposed to intersect with glycolysis and one-carbon metabolism. Although the study's conclusion is supported by solid evidence from in-vitro cellular and in-vivo mouse models, there are ...

Digital technologies and AI are disrupting the way people live, work, and learn. At the same time, education systems need to become both a rapid producer and an avid consumer of digital and data ...

Overall, digital pathways in education and skills development can be seen as the interplay of two dimensions: (1) depth of digital transitions, the extent to which public policy efforts take a ...

MANILA, Philippines — A bill to allow graduating junior high school students to pick alternative education pathways has been approved on third and final reading by the House of Representatives ...

These new pilots are referred to collectively by IRCC as Canada’s “Home Care Worker Immigration Pilots”. These pilot programs will replace the previous permanent residence (PR) pathways for caregivers ...

In 2025, Canada will unveil four new permanent residency pathways aimed at tackling labor shortages and creating more opportunities for foreign nationals. These initiatives include the Enhanced ...