A groundbreaking study indicates that linoleic acid, found in common cooking oils, may accelerate the growth of aggressive ...

Estela Jacinto, a professor of biochemistry and molecular biology at Rutgers Robert Wood Johnson Medical School, has been studying a crucial pathway for human cell growth and metabolism for more than ...

Fatty acids are unique macromolecules as they act as biological modulators of transcription factors and regulate their own metabolism by controlling the activity or abundance of transcription factors ...

Researchers looked at the ability of omega-6 fatty acids—particularly linoleic acid to drive an important, nutrient-sensing growth pathway called the mTORC1 pathway ... a major regulator of cell ...

we challenged pancreatic cancer cells with microenvironmental nutrient levels and analyzed changes in cell metabolism. We found that arginine limitation in pancreatic tumors perturbs saturated and ...

They looked at the ability of omega-6 fatty acids—particularly linoleic acid, the dominant one in the Western diet—to drive an important, nutrient-sensing growth pathway called the mTORC1 pathway ...

The beta-oxidation pathway of fatty acid and long chain acyl-CoA yields acetyl-CoA that enters the mitochondrial ... Increased concentrations of FFAs are risk factors for the development of type 2 ...

During digestion, the body breaks down fats into fatty acids, which can then be absorbed into the blood. Fatty acid molecules are usually joined together in groups of three, forming a molecule called ...

Conclusions FFAs upregulate hepatic expression of MPST and subsequently inhibit the CSE/H 2 S pathway ... fatty acids (FFAs) and their metabolites are important mediators of lipotoxicity, leading to ...