1). This mutation therefore ‘rewires’ the substrate specificity of an E3 ligase to induce aberrant degradation of proteins that are required for normal cellular function. Control of human ...

Processing is a term that introduces ambiguity and encompasses various types of processes, from simple ones such as heating or chopping to more complex ones, such as extrusion and fermentation ...

cytosolic proteins) or lysosomal (for example, internalized receptors) degradation. However, once a commitment to these degradative machines has been made, associated DUB activities can recycle ...

The new agreement will tap into Cullgen’s targeted protein degradation platform – called uSMITE – which focuses on the ubiquitin proteasome system and, specifically, ligands for E3 ligases ...

Various kinds of plant based protein. Plant-based eating has steadily ... fermented products to grocery shelves and dinner tables. Fermentation is beloved for its ability to transform ordinary ...

SPIE Photonics West is the world’s leading photonics technologies event. Thousands of people attend Photonics West each year to learn, connect, and find the latest research and products. Topics cover ...