Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. + ...

Company’s presentations highlight the power of mitochondrial medicine and protein homeostasis technologies to address ...

Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms ...

Two people in Oregon have died from a rare, progressive brain disorder similar to "mad cow disease" that leads to dementia and is %100 fatal. The Hood River County Health Department confirmed the ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease ...

Apr. 9, 2025 — A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, according to new ... Apr. 7, 2025 — A study ...

前列腺癌严重威胁男性健康，现有治疗手段存在局限。研究人员聚焦分支链氨基酸（BCAAs）及 BCAT2 在前列腺癌中的作用。发现 BCAT2 高表达与预后不良相关，其通过与 PCBP1 互作调节 PI3K/AKT 通路，影响细胞进程。该研究为前列腺癌诊疗提供新靶点和思路。

鉴于 MSL1-KTD12 轴调控 SLC7A11 的表达，研究人员推测其可能参与铁死亡过程。为验证这一假设，研究人员首先采用 MTT 检测法评估了三种不同结肠癌细胞对 I 类铁死亡诱导剂 埃拉斯汀 的敏感性。埃拉斯汀 显著诱导 HCT116 和 SW480 细胞死亡。免疫印迹分析显示，埃拉斯汀 处理的细胞中 MSL1 和 H4K16ac 水平显著降低，同时 KCTD12 表达增加，SLC7A11 ...