Thrombin mediates fibrin polymerization and is known to be involved in acute and chronic inflammatory processes in vivo. Flick et al. have used various genetically engineered mouse models to study ...

In 2023, Roche said it was removing TNKase for stroke from its phase 3 programmes after a readout of the TIMELESS trial, but ...

Fibrinolytic therapy, also known as thrombolytic therapy, is used to lyse acute blood clots by activating plasminogen, resulting in the formation of plasmin, which cleaves the fibrin cross-links ...