However, some small lengths of DNA can exist as alternative shapes, which can affect how the instructions of the DNA code is ‘read’. G-quadruplex DNA is a four-stranded structure made that can form a ...

A high resolution structure ... The DNA backbone does have the inherent ability to fold into more complex arrangements, however, as shown for example, by intramolecular triplex and quadruplex ...

Our laboratory has been interested in understanding the control of self-assembly of these architectures known as G-quadruplexes. In our studies we utilize chemical synthesis methods, biomolecular NMR ...

A specialized structure in both DNA and RNA, the G-quadruplex, consists of regulatory elements involved in gene expression in both DNA and RNA. In a new study, the researchers used theoretical ...