为解决 TTM 最佳温度及作用机制不明等问题，安徽医科大学研究人员开展 TTM 对 PRMD 影响的研究，发现 33°C 的 TTM 可减轻 PRMD，与激活 Nrf2、调节铁稳态有关。该研究为心脏骤停治疗提供新思路，值得科研读者一读。

ROS produced from oxidative phosphorylation (ETC) may cause lipid peroxidation if the activity of mitochondrial GPX4 is compromised. Export of ISC occurs with the help of mitoNEET proteins (mNT). This ...

The following is a summary of “Expression and prognostic value of ferritinophagy-related NCOA4 gene in low-grade glioma: integration of bioinformatics and experimental validation,” published in the ...

在这项研究中，团队阐明了铁变态反应的重要调节因子GPX4在半胱氨酸66上可逆地发生棕榈酰化。 2025年1月20日， 深圳湾实验室尹成骞教授团队在期刊《Nature Communications》上合作发表了题为“Palmitoylation-dependent regulation of GPX4 suppresses ferroptosis”的研究论文。

在这项研究中，团队阐明了铁变态反应的重要调节因子GPX4在半胱氨酸66上可逆地发生棕榈酰化。 2025年1月20日， 深圳湾实验室尹成骞教授团队在期刊 ...

开罗大学医学院医学生理学系的 Hanan Seddiek、Mira Hanna 等研究人员在Scientific Reports期刊上发表了题为 “Deferiprone ameliorates cisplatin-induced peripheral neurotoxicity via ferritinophagy adjustment ... 定量实时 PCR 分析细胞抗氧化相关基因（GPX4 ...

Lipid metabolism, particularly involving GPX4 and System Xc- plays a significant role in both the progression of ... Furthermore, an additional reservoir of LIP is replenished through ferritinophagy, ...

Objective Investigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment. Design Glutathione peroxidase 4 (GPx4), which is considered ...

Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China ...