ROS produced from oxidative phosphorylation (ETC) may cause lipid peroxidation if the activity of mitochondrial GPX4 is compromised. Export of ISC occurs with the help of mitoNEET proteins (mNT). This ...

开罗大学医学院医学生理学系的 Hanan Seddiek、Mira Hanna 等研究人员在Scientific Reports期刊上发表了题为 “Deferiprone ameliorates cisplatin-induced peripheral neurotoxicity via ferritinophagy adjustment ... 定量实时 PCR 分析细胞抗氧化相关基因（GPX4 ...

Objective Investigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment. Design Glutathione peroxidase 4 (GPx4), which is considered ...

印度尼西亚帕捷加兰大学医学院附属哈桑?萨迪金综合医院妇产科的 Rina Nulianti 等人，于《Scientific Reports》期刊发表了题为 “Correlation of ferritin and glutathione peroxidase 4 (GPX4) level as a marker of ferroptosis process in endometrioma” ...

Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China ...

在这项研究中，团队阐明了铁变态反应的重要调节因子GPX4在半胱氨酸66上可逆地发生棕榈酰化。 2025年1月20日， 深圳湾实验室尹成骞教授团队在期刊《Nature Communications》上合作发表了题为“Palmitoylation-dependent regulation of GPX4 suppresses ferroptosis”的研究论文。

在这项研究中，团队阐明了铁变态反应的重要调节因子GPX4在半胱氨酸66上可逆地发生棕榈酰化。 2025年1月20日， 深圳湾实验室尹成骞教授团队在期刊 ...

Department of Radiology, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210008, China ...

As a corollary, tailored interventions for ferroptosis manifest distinct paradigms, encompassing mechanisms like the modulation of the GSH/GPX4 axis, inhibition of lipid peroxidation, and chelation of ...