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News Medical
1 个月
Lithocholic acid enhances health and lifespan, mimicking calorie restriction
In LCA-treated mice, significant upregulation of plasma glucagon-like peptide 1 (GLP-1) levels was observed. LCA-treated aged mice exhibited improvements in running distance, duration, and grip ...
eLife
1 个月
Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis
We found that ADGRA3 facilitates the biogenesis of beige adipocytes through the Gs-PKA-CREB axis. Moreover, hesperetin was identified as a potential agonist of ADGRA3, capable of inducing adipocyte ...
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