Findings reveal macrophages' role in immune modulation through bacterial metabolites, paving the way for improved therapies ...

Following injury, many organs are capable of rapid regeneration of necrotic tissue to regain normal function. In contrast, ...

Hepatic ischemia-reperfusion injury (IRI) is a common and unavoidable complication associated with liver transplants that may ...

A pioneering study has revealed that increased stiffness in the extracellular matrix (ECM) of spinal discs impairs energy ...

TP53 Y220C mutations in advanced urothelial bladder cancer (UBC): A genomic landscape study. This is an ASCO Meeting Abstract from the 2025 ASCO Genitourinary Cancers Symposium. This abstract does not ...

Our approach outperforms alternatives by striking an optimal balance, evaluating enzyme expression at pathway level, rather than either single-reaction or whole-network levels. Enhanced flux potential ...

1Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, China. 2Shandong Engineering Research Center of ...

Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis revealed a significant difference in metabolic pathways between HA and S samples, including oxidative phosphorylation, glycolysis ...

That change was linked to a rise in a modified form of cholesterol known as oxysterol. Lowering oxysterol, in both animal models and human stem cells, freed the trapped ABCA1 and restored the pathway ...

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