HMGB1 that belongs to the High Mobility Group-box superfamily, is a nonhistone chromatin associated transcription factor. It is present in the nucleus of eukaryotes and can be actively secreted or ...

Immunohistochemistry (IHC) is a special test used by pathologists to detect specific molecules on cells. It is widely used in clinical oncology for categorizing solid cancer tumors and blood cancers, ...

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Background: Immunohistochemistry (IHC) is a widely used laboratory technique for cancer diagnosis, which selectively binds specific antibodies to target proteins in tissue samples and then makes the ...

On the contrary, ferroptosis triggers tumour infiltration of myeloid derived suppressor cells (MDSCs) via HMGB1 in HCC but not in colorectal cancer (CRC). Ferroptosis is as potent anticancer target ...

State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong SAR, China Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong ...

In an unusual development, five judges of the Islamabad High Court (IHC) have approached the chief justice of Pakistan and three high court chief justices, requesting them not to advise the ...

ISLAMABAD: Seven judges of the Islamabad High Court (IHC) have expressed concern over the recent media reports of a transferred judge being appointed to the IHC's top seat in a letter to chief ...

In a move widely seen as "court packing", the federal government has successfully shuffled the deck in the Islamabad High Court (IHC) by transferring three judges from other high courts – a ...