The histone tag, characterized by lysine 8 acetylation on histone H4, identifies a significant departure from the histone ...

The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

The team's findings were published in the paper "Functional reprogramming of neutrophils within the brain tumor microenvironment by hypoxia-driven histone lactylation," from Cancer Discovery. Brain ...

How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell development in chickens, the investigators started with whole chromatin from ...

In a preprint uploaded to bioRxiv this January that has yet to undergo peer review, the team describes hundreds of potential histone proteins in bacteria, including one that they predict interacts ...

Scientists discovered a way to block hepatitis B infection using an anticancer drug, offering hope for new treatments.

Shanghai Henlius Biologics Co. Ltd. has synthesized histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) and/or histone acetyltransferase KAT6B (MOZ2; MYST-4) ...

Hyper-elevated levels of RNAPII on these histone genes indicate cancer over-proliferation and potentially contribute to chromosomal changes. These findings point to the use of a new genomic ...

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes ...

Histone deacetylase 3 (HDAC3) is involved in transcriptional regulation, phosphorylation and the inhibition of tumor suppressor genes. Its upregulation in several types of tumors, such as colorectal, ...

Scientists have discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling further tumor growth.