Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...

In recent years, the combination of specific antibody-based immunoprecipitation with advanced high-resolution ... as a novel, acetoacetate-induced modification in both histone and non-histone proteins ...

University Grenoble Alpes, CEA, INSERM, UA13 BGE, CNRS, CEA, 38000 Grenoble, France ...

In 2011, Yingming Zhao’s research team identified crotonylation as a novel PTM affecting both histone and non-histone proteins (Figure 2). This modification involves the addition of a crotonyl group ...

In January 2023, Lockheed also booked a $320 million contract modification to provide non-recurring engineering services to support the production of new F-35 flight science test aircraft.

DNA methylation is predominantly involved in the silencing of gene expression. 1 Histone modification: Post-translational changes to the histone proteins that help package DNA into chromosomes.