Cell lines are used early in drug discovery and development to create relevant models that reflect human biology, in both health and disease, for in vitro research. However, engineering cell lines ...

This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...

This new cell culturing platform, known as the gut-microbiome on a chip (GMoC), provides a realistic in vitro microgut model ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

and that ultimately impinges on the reliability of the experimental findings that we get from in vitro experiments.” By lowering the media volume, and thus increasing the pericellular oxygen, Tan ...

A research team has developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of ...

A collaborative research team from POSTECH has successfully developed a gastric cancer model using 3D bioprinting technology ...

This innovative model bridges top-down and bottom-up ... importance of microenvironmental factors in shaping tumor cell behavior. In vitro experiments showed that incyclinide significantly reduced ...

The researchers used both in vivo and in vitro models to investigate the mechanisms underlying osteocyte death. They demonstrated that melanoma cells induce ... mouse model and RNA sequencing ...