Cell lines are used early in drug discovery and development to create relevant models that reflect human biology, in both health and disease, for in vitro research. However, engineering cell lines ...

This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...

An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...

These communities of microorganisms – also known collectively as the gut flora or gastrointestinal microbiome – can either help or harm us. However, the exact mechanisms by which these gut microbes ...

A research team has developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of ...

The global induced pluripotent stem cells market size is calculated at USD 2.13 billion in 2025 and is expected to reach ...

This innovative model bridges top-down and bottom-up ... importance of microenvironmental factors in shaping tumor cell behavior. In vitro experiments showed that incyclinide significantly reduced ...

and that ultimately impinges on the reliability of the experimental findings that we get from in vitro experiments.” By lowering the media volume, and thus increasing the pericellular oxygen, Tan ...

The researchers used both in vivo and in vitro models to investigate the mechanisms underlying osteocyte death. They demonstrated that melanoma cells induce ... mouse model and RNA sequencing ...