The addition of nab-paclitaxel to gemcitabine and cisplatin did not improve survival in advanced biliary tract cancer.

February is National Cancer Awareness Month, a time to amplify discussions on lesser- known but equally devastating ...

FGFR2 gene fusion is observed in approximately 14% of intrahepatic cholangiocarcinoma ... as a first-line therapy for cholangiocarcinoma in combination with chemotherapy. Eisai is also developing ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

After hours: February 19 at 4:05:02 PM EST Loading Chart for HCM ...

Cancer therapeutic resistance occurs as cancers develop resistance to treatments such as chemotherapy, radiotherapy and targeted therapies, through many different mechanisms. These include ...

The oncometabolite D-2-HG has been implicated in compromising DNA repair pathway. Here the authors show D-2-HG leads to genome-wide DNA hypermethylation and loss of CTCF coverage, which impairs ...