From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

29Developmental Biology and Cancer Department, UCL GOS Institute of Child Health, London, United Kingdom. 32Haematology and Oncology Department, Great Ormond Street Hospital, London, United Kingdom.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Diverse sets of progenitors contribute to the ...

But promising results from a recent clinical trial suggest that broadly neutralizing antibody therapy (bNAbs) may be able to accomplish the next best thing. Data from the trial—a collaboration ...

(NASDAQ: SYRE) (the "Company" or "Spyre"), a clinical-stage biotechnology company advancing best-in-class antibody engineering, dose optimization, and rational therapeutic combinations for the ...

They found that a set of three transcription factors, specifically NGN2, ISL1, and LHX3, was sufficient to induce the conversion. The researchers also conducted detailed tests to examine in detail the ...

Get Instant Summarized Text (Gist) A lupus-related antibody has been found to enhance immune responses against certain tumors by entering "cold" tumors and activating immune reactions. This ...

Dublin, March 24, 2025 (GLOBE NEWSWIRE) -- The "Antibody Drug Conjugate Market Industry Trends and Global Forecasts to 2035, by Target Disease Indication, Therapeutic Area, Linker, Payload ...

此次，团队采用直接转化策略，无需通过iPSC阶段，而是从体细胞“一步到位”变成运动神经元。优化的转化方案仅需3种转录因子（NGN2、ISL1和LHX3）配合两种促进细胞增殖的基因（编码p53DD和突变型HRAS的基因），即可实现皮肤细胞向运动神经元的高效转化。

Their paper, "A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response," was recently accepted and published in the Science Translational Medicine journal.

富含半胱氨酸的肠道蛋白（Cysteine-rich intestinal protein，CRIP）家族便是其中之一，它作为 Lin-1、Isl1、Mec3（LIM）蛋白 / 双锌指蛋白家族的一个亚家族，包含 CRIP1、CRIP2 和 CRIP3 三个成员，在生物体内发挥着多样且关键的作用。 一、CRIP 家族概述：结构域、表达及研究 ...